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How does the binding of different ligands (e.g., 17β-estradiol and anti-estrogens) affect the recruitment of co-factors to the AF-2 region of Estrogen Receptor?

14 November 2024

How does the variability in the sequence of Estrogen Response Elements (EREs) influence the conformational changes in the Estrogen Receptor (ER)?

14 November 2024

How do the zinc fingers within the DNA-binding domain (DBD) of the Estrogen Receptor (ER) influence the receptor’s ability to interact with Estrogen Response Elements (EREs)?

13 November 2024

What potential explanations exist for the presence of a common sequence in the HREs of various hormones?

11 November 2024

What is a Hormone Response Element (HRE)? Give an explanation.

10 November 2024

Understanding Nuclear Receptors: Detailed Insights into Structure, Types, and Type 1 & Type 2 Signaling Pathways

26 October 2024

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